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Product Details
| Alternate Name | 2-(4-tert-Butylphenyl)-1H-benzimidazole, 2-[4-(1,1-Dimethylethyl)phenyl]-1H-benzimidazole |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 49671-76-3 |
| Molecular Formula | C₁₇H₁₈N₂ |
| Molecular Weight | 250.34 |
| Purity | ≥95% by HPLC |
| Solubility | DMSO (~ 10 mg/ml) |
| SMILES | CC(C)(C)C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2 |
| InChi | InChI=1S/C17H18N2/c1-17(2,3)13-10-8-12(9-11-13)16-18-14-6-4-5-7-15(14)19-16/h4-11H,1-3H3,(H,18,19) |
| InChi Key | LQUNNCQSFFKSSK-UHFFFAOYSA-N |
| PubChem CID | 899323 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
ZLN005 is a small molecule transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α). It stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM. ZLN005 increases fat oxidation and improves the glucose tolerance, pyruvate tolerance, and insulin sensitivity of diabetic db/db mice.
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