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ZLN005

Atranscriptional regulator of PGC1-α
Catalog #: 2550
SKU-Size Size Price Qty
2550-10 10 mg
$65.00
2550-50 50 mg
$255.00
More Sizes Get Quote

Product Details

Alternate Name 2-(4-tert-Butylphenyl)-1H-benzimidazole, 2-[4-(1,1-Dimethylethyl)phenyl]-1H-benzimidazole
Appearance White to off-white solid
CAS # 49671-76-3
Molecular Formula C₁₇H₁₈N₂
Molecular Weight 250.34
Purity ≥95% by HPLC
Solubility DMSO (~ 10 mg/ml)
SMILES CC(C)(C)C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2
InChi InChI=1S/C17H18N2/c1-17(2,3)13-10-8-12(9-11-13)16-18-14-6-4-5-7-15(14)19-16/h4-11H,1-3H3,(H,18,19)
InChi Key LQUNNCQSFFKSSK-UHFFFAOYSA-N
PubChem CID 899323
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

ZLN005 is a small molecule transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α). It stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM. ZLN005 increases fat oxidation and improves the glucose tolerance, pyruvate tolerance, and insulin sensitivity of diabetic db/db mice.


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