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Zebularine

A DNA methylation inhibitor
Catalog #: 2225
SKU-Size Size Price Qty
2225-1 1 mg
$55.00
2225-5 5 mg
$125.00
More Sizes Get Quote

Product Details

Alternate Name 1H-​β-​D-​ribofuranosyl-​2-​pyrimidinone; NSC 309132
Appearance White solid
CAS # 3690-10-6
Molecular Formula C₉H₁₂N₂O₅
Molecular Weight 228.2
Purity ≥98% by HPLC
Solubility DMSO (100 mM) or H2O (100 mM)
SMILES C1=CN(C(=O)N=C1)C2C(C(C(O2)CO)O)O
InChi InChI=1S/C9H12N2O5/c12-4-5-6(13)7(14)8(16-5)11-3-1-2-10-9(11)15/h1-3,5-8,12-14H,4H2/t5-,6-,7-,8-/m1/s1
InChi Key RPQZTTQVRYEKCR-WCTZXXKLSA-N
PubChem CID 100016
MDL Number MFCD04973699
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Zebularine is a potent inhibitor of cytidine deaminase and DNA methylation; inhjbits DNA methylation by forming a covalent complex with DNA methyltransferases (DNMTs). Displays antitumor properties.


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