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Zalcitabine

An antiviral agent
Catalog #: B2796
SKU-Size Size Price Qty
B2796-50 50 mg
$75.00
B2796-250 250 mg
$275.00
More Sizes Get Quote

Product Details

Alternate Name Ro 24-2027/000; Hivid; NSC-606170; ddC; 2′,3′-Dideoxycytidine
Peptide Sequence N/A
Appearance White to off-white solid
CAS # 7481-89-2
Molecular Formula C₉H₁₃N₃O₃
Molecular Weight 211.22
Purity ≥98%
Solubility ~0.2 mg/ml DMSO
SMILES C1CC(OC1CO)N2C=CC(=NC2=O)N
InChi InChI=1S/C9H13N3O3/c10-7-3-4-12(9(14)11-7)8-2-1-6(5-13)15-8/h3-4,6,8,13H,1-2,5H2,(H2,10,11,14)/t6-,8+/m0/s1
InChi Key WREGKURFCTUGRC-POYBYMJQSA-N
PubChem CID 24066
MDL Number MFCD00012188
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Zalcitabine is an antiviral pyrimidine nucleoside analog effective against HIV replication. In cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered


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