Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


based on 7 citations in multiple journalsZ-LEVD-FMK74.1 4
A caspase-4 inhibitor
Catalog #: 1144
SKU-Size Size Price Qty
1144-1 1 mg
1144-5 5 mg
More Sizes Get Quote

Product Details

Alternate Name Z-LEVD-FMK, Z-LEVD-fluoromethylketone, Caspase-4 Inhibitor (fluoromethylketone)
Peptide Sequence Z-Leu-Glu(OMe)-Val-Asp(OMe)-FMK
Appearance Lyophilized solid
Molecular Formula C₃₁H₄₅FN₄O₁₀
Molecular Weight 652.7
Purity Single spot by TLC
Solubility DMSO (20 mM)
InChi InChI=1S/C31H45FN4O10/c1-18(2)14-23(35-31(43)46-17-20-10-8-7-9-11-20)29(41)33-21(12-13-25(38)44-5)28(40)36-27(19(3)4)30(42)34-22(24(37)16-32)15-26(39)45-6/h7-11,18-19,21-23,27H,12-17H2,1-6H3,(H,33,41)(H,34,42)(H,35,43)(H,36,40)
PubChem CID 44135220
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A synthetic peptide that irreversibly inhibits activity of LEVD-dependent caspases (e.g., caspase-4). The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.
Youn Jung Choi, SERPINB1-mediated checkpoint of inflammatory caspase activation. Nat Immunol., Jan 2019; 30692621.
Burm et al., Inflammasome-Induced IL-1β Secretion in Microglia Is Characterized by Delayed Kinetics and Is Only Partially Dependent on Inflammatory Caspases. J. Neurosci., Jan 2015; 35: 678 - 687.
Eric A. Ariazi, et. al. Inaugural Article: Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time. PNAS, Nov 2011; 108: 18879 - 18886.
Binet, F. et. al. Interaction between arsenic trioxide (ATO) and human neutrophils. Human and Experimental Toxicology, May 2011; 30: 416 - 424.
Rosati, E. et al. Novel Targets for Endoplasmic Reticulum Stress-Induced Apoptosis in B-CLL. Blood, 2010; 116: 2713-2723.
For more citations of this product click here