A caspase-9 inhibitor
Catalog #: 1149 | abID:

Product Details

Alternate Name Z-LEHD-FMK, Z-LEHD-fluoromethylketone, Caspase-9 Inhibitor (fluoromethylketone)
Peptide Sequence Z-Leu-Glu(OMe)-His-Asp(OMe)-FMK
Appearance Lyophilized solid
Molecular Formula C₃₂H₄₃FN₆O₁₀
Molecular Weight 690.71
Purity Single spot by TLC
Solubility DMSO (20 mM)
InChi InChI=1S/C32H43FN6O10/c1-19(2)12-24(39-32(46)49-17-20-8-6-5-7-9-20)30(44)36-22(10-11-27(41)47-3)29(43)38-25(13-21-16-34-18-35-21)31(45)37-23(26(40)15-33)14-28(42)48-4/h5-9,16,18-19,22-25H,10-15,17H2,1-4H3,(H,34,35)(H,36,44)(H,37,45)(H,38,43)(H,39,46)
PubChem CID 44135217
MDL Number MFCD01862609
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

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