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Z-AEVD-FMK

A caspase-10 inhibitor
Catalog #: B1162
SKU-Size Size Price Qty
B1162-1 1 mg
$265.00
B1162-5 5 mg
$795.00
More Sizes Get Quote

Product Details

Alternate Name Z-A-E(OMe)-V-Asp(OMe)-FMK; Z-Ala-Glu(OMe)-Val-Asp(OMe)-FMK; Z-Ala-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone; FK033
Peptide Sequence Z-Ala-Glu(OMe)-Val-Asp(OMe)-FMK
Appearance Lyophilized solid
CAS # 1135688-47-9
Molecular Formula C₂₈H₃₉FN₄O₁₀
Molecular Weight 610.63
Purity ≥95% by HPLC
Solubility DMSO (~ 10 mg/ml)
SMILES CC(C)C(C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CCC(=O)OC)NC(=O)C(C)NC(=O)OCC1=CC=CC=C1
InChi InChI=1S/C28H39FN4O10/c1-16(2)24(27(39)32-20(21(34)14-29)13-23(36)42-5)33-26(38)19(11-12-22(35)41-4)31-25(37)17(3)30-28(40)43-15-18-9-7-6-8-10-18/h6-10,16-17,19-20,24H,11-15H2,1-5H3,(H,30,40)(H,31,37)(H,32,39)(H,33,38)/t17-,19-,20-,24-/m0/s1
InChi Key CHZRBQFKZDGMTP-CDSYHYPYSA-N
PubChem CID 25108694
MDL Number MFCD03453601
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Z-AEVD-FMK is a synthetic peptide inhibitor that inhibits caspase-10 and related caspase activity. FMK inhibitors are irreversible and non-toxic, and can be used in both in vivo and in vitro studies. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).


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