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Product Details
| Alternate Name | 4-[(1Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol; 4-OH-TAM |
|---|---|
| Appearance | White solid |
| CAS # | 68047-06-3 |
| Molecular Formula | C₂₆H₂₉NO₂ |
| Molecular Weight | 387.51 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (>35 mg/ml) or H2O (>10 mg/ml) |
| SMILES | CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3 |
| InChi | InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25- |
| InChi Key | TXUZVZSFRXZGTL-QPLCGJKRSA-N |
| PubChem CID | 449459 |
| MDL Number | MFCD00278780 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
(Z)-4-Hydroxytamoxifen is a metabolite of Tamoxifen (Cat. No. 1551); acts as a potent estrogen receptor antagonist. Displays more potency than the parent compound. Also activates intein-linked inactive Cas9, reducing off-target CRISPR-mediated gene editing.
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