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Y-27632, dihydrochloride

A Rho kinase (ROCK) inhibitor
Catalog #: 1596
SKU-Size Size Price Qty
1596-1 1 mg
$125.00
1596-5 5 mg
$400.00
1596-50 50 mg
$2,325.00
More Sizes Get Quote

Product Details

Alternate Name trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecar boxamide dihydrochloride
Appearance White soild
CAS # 129830-38-2
Molecular Formula C₁₄H₂₁N₃O.2HCl
Molecular Weight 320.26
Purity ≥99% by HPLC
Solubility H₂O (100 mM) or PBS (100 mM)
SMILES CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
InChi InChI=1S/C14H21N3O.2ClH/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13;;/h6-12H,2-5,15H2,1H3,(H,16,17,18);2*1H/t10-,11?,12?;;/m1../s1
InChi Key IDDDVXIUIXWAGJ-DDSAHXNVSA-N
PubChem CID 9901617
MDL Number MFCD03490488
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Selective inhibitor of the Rho-associated protein kinase p160ROCK. Ki values are 0.14, 26, 25 and >250 µM for p160ROCK, PKC, cAMP-dependent protein kinase and myosin light-chain kinase, respectively. Prevents apoptosis as well as enhance the survival and cloning efficiency of dissociated human embryonic stem cells (hES) without affecting their pluripotency.


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