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XY1

An inactive control of SGC707
Catalog #: B2850
SKU-Size Size Price Qty
B2850-5 5 mg
$175.00
B2850-25 25 mg
$675.00
More Sizes Get Quote

Product Details

Alternate Name 1-naphthalen-2-yl-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea; N-2-Naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea
Appearance A crystalline solid
CAS # 1624117-53-8
Molecular Formula C₁₇H₁₉N₃O₂
Molecular Weight 297.35
Purity ≥98%
Solubility ~10 mg/ml in DMF
~25 mg/ml in DMSO
SMILES C1CCN(C1)C(=O)CNC(=O)NC2=CC3=CC=CC=C3C=C2
InChi InChI=1S/C17H19N3O2/c21-16(20-9-3-4-10-20)12-18-17(22)19-15-8-7-13-5-1-2-6-14(13)11-15/h1-2,5-8,11H,3-4,9-10,12H2,(H2,18,19,22)
InChi Key GSQHGSRPQHBTTP-UHFFFAOYSA-N
PubChem CID 78871801
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

XY1 is an inactive control of SGC707. SGC707 is a potent, selective and allosteric inhibitor of Protein arginine methyltransferase3 (PRMT3) with an IC₅₀ of 31 nM. It inhibits the methylation of histones in cells at a concentration of 1 µM. XY1 is an analog of SGC707 that is completely inactive against PRMT3 at concentrations as high as 100 µM.


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