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XL-147

A PI3K inhibitor
Catalog #: B3352
SKU-Size Size Price Qty
B3352-5 5 mg
$125.00
B3352-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name SAR245408 Pilaralisib 2-amino-N-[3-[[[3-[(2-chloro-5-methoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-2-methyl-propanamide
Appearance Solid
CAS # 934526-89-3
Molecular Formula C₂₅H₂₅ClN₆O₄S
Molecular Weight 541.02
Purity ≥98%
Solubility >40 mg/ml DMSO
SMILES CC(C)(C(=O)NC1=CC(=CC=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=C(C=CC(=C4)OC)Cl)N
InChi InChI=1S/C25H25ClN6O4S/c1-25(2,27)24(33)28-15-7-6-8-17(13-15)37(34,35)32-23-22(29-19-9-4-5-10-20(19)30-23)31-21-14-16(36-3)11-12-18(21)26/h4-14H,27H2,1-3H3,(H,28,33)(H,29,31)(H,30,32)
InChi Key QINPEPAQOBZPOF-UHFFFAOYSA-N
PubChem CID 56599306
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

XL-147 is a potent and reversible Class 1 PI3-kinase family inhibitor with potential antineoplastic activity. Inactivation of PI3K has been shown to inhibit growth and induce apoptosis (programmed cell death) in tumor cells.


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