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Wortmannin, Penicillium funiculosum

A PI3 Kinase inhibitor
Catalog #: 1670
$80.00

Product Details

Cat # +Size 1670-1
Size 1 mg
Alternate Name KY 12420
Appearance Off-white solid
CAS # 19545-26-7
Molecular Formula C₂₃H₂₄O₈
Molecular Weight 428.44
Purity ≥98% by HPLC
Solubility DMSO (50 mM) or EtOH (5 mM)
SMILES CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C5=COC(=C54)C3=O)COC)C)C
InChi InChI=1S/C23H24O8/c1-10(24)30-13-7-22(2)12(5-6-14(22)25)16-18(13)23(3)15(9-28-4)31-21(27)11-8-29-20(17(11)23)19(16)26/h8,12-13,15H,5-7,9H2,1-4H3/t12-,13+,15+,22-,23-/m0/s1
InChi Key QDLHCMPXEPAAMD-QAIWCSMKSA-N
PubChem CID 312145
MDL Number MFCD00133927
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Potent, selective, cell-permeable and irreversible inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) (IC₅₀ = 2-4 nM). Also potently inhibits polo-like kinase 1 (PLK1) (IC₅₀ = 5.8 nM).


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