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Wogonoside

Flavonoid with antioxidant, anti-cancer and anti-angiogenic activity
Catalog #: B2953
SKU-Size Size Price Qty
B2953-5 5 mg
$95.00
B2953-25 25 mg
$380.00
More Sizes Get Quote

Product Details

Alternate Name Wogonin 7-O-glucuronide; Oroxindin; (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(5-hydroxy-8-methoxy-4-oxo-2-phenylchromen-7-yl)oxyoxane-2-carboxylic acid; 5,7-dihydroxy-8-methoxyflavone 7-O-beta-D-glucuronide; 5-hydroxy-8-methoxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid; Glychionide B; Wogonin 7-O-β-D-Glucuronopyranoside
Appearance Solid
CAS # 51059-44-0
Molecular Formula C₂₂H₂₀O₁₁
Molecular Weight 460.39
Purity ≥95%
Solubility Soluble in DMSO
SMILES COC1=C(C=C(C2=C1OC(=CC2=O)C3=CC=CC=C3)O)OC4C(C(C(C(O4)C(=O)O)O)O)O
InChi InChI=1S/C22H20O11/c1-30-18-13(32-22-17(27)15(25)16(26)20(33-22)21(28)29)8-11(24)14-10(23)7-12(31-19(14)18)9-5-3-2-4-6-9/h2-8,15-17,20,22,24-27H,1H3,(H,28,29)/t15-,16-,17+,20-,22+/m0/s1
InChi Key LNOHXHDWGCMVCO-NTKSAMNMSA-N
PubChem CID 3084961
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Wogonoside is a flavonoid with antioxidant, anti-cancer and anti-angiogenic activity. Wogonoside inhibits the growth of U937 and HL-60 cells cells. It arrests the cell cycle at the G0/G1 phase and decreases the G2/M and S phases in these cells in a dose dependent manner at concentrations of 50 μM, 100 μM, and 150 μM. It inhibits LPS-induced angiogenesis by inhibiting the toll-like receptor 4 upregulation.


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