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Wnt Antagonist, C59

based on 3 citations in multiple journalsWnt Antagonist, C5934.1 4
A potent Wnt signaling pathway inhibitor
Catalog #: 2063
SKU-Size Size Price Qty
2063-1 1 mg
$80.00
2063-5 5 mg
$285.00
More Sizes Get Quote

Product Details

Alternate Name 2-(4-(2-Methylpyridin-4-yl)phenyl)-N-4-(pyridin-3-yl)phenyl)acetamide
Appearance Pale yellow solid
CAS # 1243243-89-1
Molecular Formula C₂₅H₂₁N₃O
Molecular Weight 379.45
Purity ≥97% by HPLC
Solubility DMSO
PubChem CID
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. A potent Wnt signaling pathway inhibitor (IC₅₀ = <0.11 nM using Wnt-Luc reporter assay).


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Chevillard-Briet et al., Interplay between chromatin-modifying enzymes controls colon cancer progression through Wnt signaling. Hum. Mol. Genet., Apr 2014; 23: 2120 - 2131.
Chevillard-Briet et al., Interplay between chromatin-modifying enzymes controls colon cancer progression through Wnt signaling. Hum. Mol. Genet., Dec 2013; 10.1093/hmg/ddt604.
David M. Virshup et al., Pharmacological Inhibition of the Wnt Acyltransferase PORCN Prevents Growth of WNT-Driven Mammary Cancer. Cancer Res., Jan 2013; 73: 502 - 507
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