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WM-1119

A potent, selective inhibitor of lysine acetyltransferase KAT6A
Catalog #: B2418

In stock

SKU-Size Size Price Qty
B2418-5 5 mg
$175.00
B2418-25 25 mg
$695.00
More Sizes Get Quote

Product Details

Alternate Name WM1119, Benzoic acid, 3-fluoro-5-(2-pyridinyl)-, 2-[(2-fluorophenyl)sulfonyl]hydrazide
Appearance Crystalline solid
CAS # 2055397-28-7
Molecular Formula C₁₈H₁₃F₂N₃O₃S
Molecular Weight 389.38
Purity ≥98% by HPLC
Solubility >40 mg/ml in DMSO
SMILES C1=CC=C(C(=C1)F)S(=O)(=O)NNC(=O)C2=CC(=CC(=C2)C3=CC=CC=N3)F
InChi InChI=1S/C18H13F2N3O3S/c19-14-10-12(16-6-3-4-8-21-16)9-13(11-14)18(24)22-23-27(25,26)17-7-2-1-5-15(17)20/h1-11,23H,(H,22,24)
InChi Key QLXULUNLCRKWRD-UHFFFAOYSA-N
PubChem CID 133080719
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

WM-1119 is a potent, reversible, and competitive inhibitor of lysine acetyltransferase KAT6A ( Kd = 2 nM). Displays 1,100-fold and 250-fold selectivity over KAT5 and KAT7, respectively; causes cell cycle arrest in G1 and senescence phenotype similar to WM-8014.


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