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A potent JAK3 inhibitor
Catalog #: 2659
SKU-Size Size Price Qty
2659-5 5 mg
2659-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name 2-Bromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenol
Appearance White to off-white solid
CAS # 211555-04-3
Molecular Formula C₁₆H₁₄BrN₃O₃
Molecular Weight 376.2
Purity ≥98% by HPLC
Solubility DMSO (>35 mg/ml)
InChi InChI=1S/C16H14BrN3O3/c1-22-14-6-10-12(7-15(14)23-2)18-8-19-16(10)20-9-3-4-13(21)11(17)5-9/h3-8,21H,1-2H3,(H,18,19,20)
PubChem CID 3795
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


WHI-P154 is a potent JAK3 inhibitor (IC₅₀ of 1.8 μM). It displays no activity against JAK1 or JAK2. Also inhibits EGFR, Src, Abl, VEGFR and MAPK, and prevents Stat3, but not Stat5 phosphorylation. Induces differentiation of neural progenitor cells

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