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WHI-P131

A JAK3 inhibitor
Catalog #: 1853
SKU-Size Size Price Qty
1853-5 5 mg
$130.00
1853-25 25 mg
$415.00
More Sizes Get Quote

Product Details

Alternate Name 4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol
Appearance White to off-white solid
CAS # 202475-60-3
Molecular Formula C₁₆H₁₅N₃O₃
Molecular Weight 297.31
Purity ≥98% by TLC
Solubility DMSO (~50mg/ml
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC
InChi InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19)
InChi Key HOZUXBLMYUPGPZ-UHFFFAOYSA-N
PubChem CID 3794
MDL Number MFCD11045992
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. Selectively inhibits the tyrosine kinase activity of Jak3 with an IC₅₀ value of 78 µM without affecting the enzymatic activity of JAK1, JAK2, or other protein tyrosine kinases. Also helps to induce rat bone marrow stromal cells (MSCs) to neuronal cells.


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