Product Details
| Alternate Name | 4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 202475-60-3 |
| Molecular Formula | C₁₆H₁₅N₃O₃ |
| Molecular Weight | 297.31 |
| Purity | ≥98% by TLC |
| Solubility | DMSO (~50mg/ml |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC |
| InChi | InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19) |
| InChi Key | HOZUXBLMYUPGPZ-UHFFFAOYSA-N |
| PubChem CID | 3794 |
| MDL Number | MFCD11045992 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Cell-permeable. Selectively inhibits the tyrosine kinase activity of Jak3 with an IC₅₀ value of 78 µM without affecting the enzymatic activity of JAK1, JAK2, or other protein tyrosine kinases. Also helps to induce rat bone marrow stromal cells (MSCs) to neuronal cells.
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