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WEHI-539

A potent and selective BCL-XL inhibitor
Catalog #: B1818

In stock

SKU-Size Size Price Qty
B1818-5 5 mg
$115.00
B1818-25 25 mg
$455.00

Product Details

Alternate Name (E)-5-(3-(4-(aminomethyl)phenoxy)propyl)-2-(8-(2-(benzo[d]thiazol-2-yl)hydrazono)-5,6,7,8-tetrahydronaphthalen-2-yl)thiazole-4-carboxylic acid
Appearance Crystalline solid
CAS # 1431866-33-9
Molecular Formula C₃₁H₂₉N₅O₃S₂
Molecular Weight 583.72
Purity ≥98% by HPLC
Solubility DMSO
SMILES C1CC2=C(C=C(C=C2)C3=NC(=C(S3)CCCOC4=CC=C(C=C4)CN)C(=O)O)C(=NNC5=NC6=CC=CC=C6S5)C1
InChi InChI=1S/C31H29N5O3S2/c32-18-19-10-14-22(15-11-19)39-16-4-9-27-28(30(37)38)34-29(40-27)21-13-12-20-5-3-7-24(23(20)17-21)35-36-31-33-25-6-1-2-8-26(25)41-31/h1-2,6,8,10-15,17H,3-5,7,9,16,18,32H2,(H,33,36)(H,37,38)/b35-24+
InChi Key JKMWZKPAXZBYEH-JWHWKPFMSA-N
PubChem CID 71297207
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

WEHI-539 is a highly potent and selective BCL-XL inhibitor (IC₅₀ = 1.1 nM).


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