Product Details
| abID | ab287124 |
|---|---|
| Alternate Name | 5-(Phenylsulfonyl)-N-4-piperidinyl-2-(trifluoromethyl)benzene sulfonamide; WAY316606 |
| Appearance | Crystalline solid |
| CAS # | 915759-45-4 |
| Molecular Formula | C₁₈H₁₉F₃N₂O₄S₂ |
| Molecular Weight | 448.48 |
| Purity | ≥98% by HPLC |
| Solubility | >40 mg/ml DMSO |
| SMILES | C1CNCCC1NS(=O)(=O)C2=C(C=CC(=C2)S(=O)(=O)C3=CC=CC=C3)C(F)(F)F |
| InChi | InChI=1S/C18H19F3N2O4S2/c19-18(20,21)16-7-6-15(28(24,25)14-4-2-1-3-5-14)12-17(16)29(26,27)23-13-8-10-22-11-9-13/h1-7,12-13,22-23H,8-11H2 |
| InChi Key | ITBGJNVZJBVPLJ-UHFFFAOYSA-N |
| PubChem CID | 16727102 |
| Handling | Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
WAY-316606 is a secreted Frizzled-Related Protein-1 (sFRP-1) inhibitor (IC₅₀ = 0.65 μM). It blocks sFRP-1 from interacting with Wnt and thus increases Wnt signaling.
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