Product Details
| Alternate Name | N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide |
|---|---|
| Appearance | Off-white solid |
| CAS # | 1161205-04-4 |
| Molecular Formula | C₁₃H₁₁ClN₂O₂ |
| Molecular Weight | 262.69 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (>20 mg/ml) |
| SMILES | COC1=C(C=CC(=C1)NC(=O)C2=CC=CC=N2)Cl |
| InChi | InChI=1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17) |
| InChi Key | ARYUXFNGXHNNDM-UHFFFAOYSA-N |
| PubChem CID | 44191096 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
VU 0361737 is a selective, brain-permeable, positive allosteric modulator at mGlu4 receptors (EC₅₀ values are 240 and 110 nM at human and rat receptors respectively). Inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors and displays weak activity at mGlu5 and mGlu8 receptors.
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