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Voglibose

A competitive α-glucosidase inhibitor
Catalog #: B2111

In stock

SKU-Size Size Price Qty
B2111-10 10 mg
$75.00
B2111-50 50 mg
$285.00
More Sizes Get Quote

Product Details

Alternate Name 3,4-Dideoxy-4-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-D-epi-inositol, N-(1,3-Dihydroxyprop-2-yl)valiolamine; AO-128
Appearance White to off-white solid
CAS # 83480-29-9
Molecular Formula C₁₀H2₂₁NO₇
Molecular Weight 267.3
Purity ≥98%
Solubility DMSO (~10 mg/ml) or H₂O (~20 mg/ml)
SMILES C1C(C(C(C(C1(CO)O)O)O)O)NC(CO)CO
InChi InChI=1S/C10H21NO7/c12-2-5(3-13)11-6-1-10(18,4-14)9(17)8(16)7(6)15/h5-9,11-18H,1-4H2/t6-,7-,8+,9-,10-/m0/s1
InChi Key FZNCGRZWXLXZSZ-CIQUZCHMSA-N
PubChem CID 444020
MDL Number MFCD00865496
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Voglibose is a competitive α-glucosidase inhibitor (IC₅₀ = 5.6 µM). It delays the absorption and digestion of dietary polysaccharides by reversibly inhibiting digestive enzymes such as maltase, isomaltase, and sucrase with IC₅₀ values of 0.18, 5.2, and 0.37 µM, respectively. Voglibose is also known to increase glucagon-like peptide 1 release.


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