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A small molecule which is cytotoxic to quiescent cancer cells
Catalog #: B2849
SKU-Size Size Price Qty
B2849-1 1 mg
B2849-5 5 mg
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Product Details

Alternate Name 6-methyl-N-[(E)-1-pyridin-2-ylethylideneamino]-5H-[1,2,4]triazino[5,6-b]indol-3-amine; 6-Methyl-3-((2E)-2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)-5H-(1,2,4)triazino(5,6-b)indole; Ethanone, 1-(2-pyridinyl)-, 2-(6-methyl-5H-1,2,4-triazino(5,6-b)indol-3-yl)hydrazone
Appearance A crystalline solid
CAS # 327031-55-0
Molecular Formula C₁₇H₁₅N₇
Molecular Weight 317.35
Purity ≥95%
Solubility ~1 mg/ml in Ethanol
~20 mg/ml in DMSO and DMF
InChi InChI=1S/C17H15N7/c1-10-6-5-7-12-14(10)19-16-15(12)22-24-17(20-16)23-21-11(2)13-8-3-4-9-18-13/h3-9H,1-2H3,(H2,19,20,23,24)/b21-11+
PubChem CID 6410104
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


VLX600 is a small molecule which is cytotoxic to quiescent cells in colon cancer cells with an IC₅₀ of 1-10 μM. VLX600 decreases mitochondrial oxidative phosphorylation and shows enhanced cytotoxic activity under conditions of nutrient starvation. It inhibits growth of colon cancer xenografts with minimal systemic toxicity in mice.

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