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Vitronectin, Human Plasma

A glycoprotein promoting cell adhesion and spreading
Catalog #: 4087
$375.00

Product Details

Cat # +Size 4087-100
Size 100 μg
Alternate Name S- protein, Serum-spreading factor, V75
Gene Symbol VTN
Gene ID 7448
Accession # P04004
Source Human plasma
Appearance Lyophilized protein
Physical Form Description Lyophilized from 10 mM sodium phosphate, pH 7.7
Molecular Weight 75.0 kDa
Purity by SDS-PAGE ≥95%
Reconstitution Instructions Reconstitute in H₂O or aqueous buffers to a concentration not less than 0.1 mg/ml. Aliquot and store at –20°C. Avoid freeze-thaw cycles.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Vitronectin and plasminogen activator inhibitor type 1 are proteins that interact in the circulatory system and pericellular region to regulate fibrinolysis, cell adhesion, and migration. Plasminogen activator inhibitor type 1, a serine proteinase, through its binding to the plasma protein vitronectin, influences processes that are key regulators of hemostatic process, for example, thrombosis and wound healing. In addition, the vitronectin and plasminogen activator inhibitor type 1 complex regulates binding of blood platelets and cells to extracellular substrata in events like tumor metastasis. The plasma concentration of vitronectin is 200 to 400 μg/ml.


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