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Visfatin, Rat Recombinant

A cytokine that promotes B cell maturation and inhibits neutrophil apoptosis
Catalog #: 4909
SKU-Size Size Price Qty
4909-10 10 μg
4909-50 50 μg
4909-1000 1 mg
More Sizes Get Quote

Product Details

Alternate Name Nicotinamide phosphoribosyltransferase, Pre-B-cell colony-enhancing factor 1 homolog, NAmPRTase, Nampt, PBEF
Gene Symbol NAMPT
Gene ID 297508
Accession # Q80Z29
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized with no additives
Molecular Weight 53.0 kDa
Purity by SDS-PAGE ≥95%
Endotoxin Level <0.1 ng/μg
Reconstitution Instructions Reconstitute in PBS to the concentration of 0.1-1 mg/ml.
Amino Acid Sequence Amino acids 1 to 491 (per UniProt Q80Z29)
Storage and Handling For maximum product recovery, centrifuge the vial prior to opening. After reconstitution in PBS, aliquot and store at –20 °C. Stable for up to 3 months. Avoid freeze/thaw cycle.
USAGE For Research Use Only! Not to be used in humans


Nicotinamide phosphoribosyltransferase (NAMPT), also known as visfatin or pre-B-cell colony enhancing factor, is a protein that catalyzes the formation of nicotinamide mononucleotide as part of the biosynthetic pathway that produces nicotinamide adenine dinucleotide (NAD). This protein is thought to be involved in many important biological processes, including metabolism, stress response, and aging. The secreted form of the protein acts as a cytokine to promote B cell maturation and inhibits neutrophil apoptosis. Visfatin operates as a circadian clock modulator through NAD-mediated oscillation of clock target gene expression such as CLOCK and ARNTL through a SIRT1-mediated mechanism.

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