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An irreversible inhibitor of GABA Transaminase
Catalog #: B2983
SKU-Size Size Price Qty
B2983-5 5 mg
B2983-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name 4-aminohex-5-enoic acid; γ-Vinyl GABA; γ-Vinyl-γ-Aminobutyric Acid; Vigabatrine; Sabril; Sabrilex; GABA Transaminase Inhibitor
Appearance White solid
CAS # 68506-86-5, 60643-86-9
Molecular Formula C₆H₁₁NO₂
Molecular Weight 129.16
Purity 98%
Solubility ~10 mg/ml in PBS, pH 7.2
InChi InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)
PubChem CID 5665
MDL Number MFCD00274577
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20 °C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


Vigabatrin (VGB) is a structural analogue of gamma-aminobutyric acid (GABA) that irreversibly inhibits GABA-transaminase (GABA-T). It inhibits the catabolism of GABA by GABA transaminase and increases GABA levels in the brain. Focal drug delivery into the subthalamic nucleus is beneficial in epilepsy and shows lesser side effects.

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