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Verapamil hydrochloride

A L-type calcium channel blocker
Catalog #: 2861
SKU-Size Size Price Qty
2861-1G 1 g
$75.00
2861-5G 5 g
$255.00
More Sizes Get Quote

Product Details

Alternate Name α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile hydrochloride
Appearance White solid
CAS # 152-11-4
Molecular Formula C₂₇H₃₈N₂O₄.HCl
Molecular Weight 491.07
Purity ≥98% by HPLC
Solubility Water (>40 mg/ml) or DMSO (>20 mg/ml) or EtOH (>20 mg/ml)
SMILES CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl
InChi InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H
InChi Key DOQPXTMNIUCOSY-UHFFFAOYSA-N
PubChem CID 62969
MDL Number MFCD0005528
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Verapamil is a L-type Calcium channel blocker. It has both peripheral and coronary vasodilator effects (IC₅₀ = 0.38 μM in guinea pig aortic strip) and has been used to control hypertension, angina, cardiac arrhythmia, and vascular headaches. Verapamil also acts as an inhibitor of drug efflux pump proteins such as P-glycoprotein, which are often over-expressed in certain tumor cell line.


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