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VEGF165, human recombinant

based on 6 citations in multiple journalsVEGF165, human recombinant64.1 4
A signal protein that stimulates vasculogenesis and angiogenesis
Catalog #: 4363
SKU-Size Size Price Qty
4363-10 10 μg
$210.00
4363-50 50 μg
$625.00
4363-1000 1 mg
$3,780.00
More Sizes Get Quote

Product Details

Alternate Name Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen
Gene Symbol VEGFA
Gene ID 7422
Accession # Q96KJ0
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized with no additives
Molecular Weight 38.2 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity Determined by the dose-dependent stimulation of the proliferation of human μmbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-7.0 ng/ml.
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
USAGE For Research Use Only! Not to be used in humans

Details

VEGF (Vascular Endothelial Growth Factor) is a secreted homodimeric protein, secreted by a variety of Vascularized tissues. VEGF stimulates endothelial cell growth, angiogenesis, and capillary permeability. Human VEGF is a 38.2 kDa homodimeric protein consisting of two 165 amino acid polypeptide chains.


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Farajpour et al., Identification and In Vitro Characterization of Phage-Displayed VHHs Targeting VEGF.J Biomol Screen, Apr 2014; 19: 547 - 555.
Peter J. Amos  et al., Hypoxic culture and in vivo inflammatory environments affect the assumption of pericyte characteristics by human adipose and bone marrow progenitor cells, Am J Physiol Cell Physiol, Dec 2011; 301: C1378 - C1388.
Anderson CR et al (2008) Am. J. Pathol. 173: 1220 1228.
Amos PJ et al (2008) Stem Cells,; 26: 2682 - 2690.
Balthasar S et al (2008) Endocr. Relat. Cancer, 15: 521-534.
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