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VEGF120, murine recombinant

A signaling protein involved in both vasculogenesis and angiogenesis
Catalog #: 4964
SKU-Size Size Price Qty
4964-10 10 μg
$240.00
4964-100 100 μg
$773.00
4964-1000 1 mg
$6,435.00
More Sizes Get Quote

Product Details

Alternate Name Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609.
Gene Symbol VEGFA
Gene ID 22339
Accession # Q00731
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Molecular Weight 28.4 kDa
Purity by SDS-PAGE ≥95%
Purity by ≥95%
Endotoxin Level ≤ 1 EU/μg
Biological Activity The activity as determined by dose-dependent proliferation of human umbilical vein endothelial cells (HUVEC) was typically found to be 1-5 ng/ml (≥ 2.0 x 105 units/mg)
Reconstitution Instructions Reconstitute the lyophilized product with sterile H₂O at a concentration of 0.1 – 0.5 mg/ml, which can be further diluted into other aqueous solutions
Amino Acid Sequence MAPTTEGEQKSHE VIKFMDVYQRSYC RPIETLVDIFQEYP DEIEYIFKPSCVPLM RCAGCCNDEALEC VPTSESNITMQIMR IKPHQSQHIGEMSFL QHSRCECRPKKD RTKPEKCDKPRR
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
USAGE For Research Use Only! Not to be used in humans

Details

Vascular Endothelial Growth factor-A (VEGF-A) was originally isolated from tumor cells and is produced by a wide variety of cell types. In addition to stimulating vascular growth and permeability, VEGF-A may play a role in stimulating vasodilatation via nitric oxide-dependent pathways. Mouse VEGF-A has several variants, one being VEGF-120 (also known as VEGF-2). Recombinant Mouse VEGF-120 is a homodimer with a molecular weight of 28.2 kDa.


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