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Valsartan

A high affinity angiotensin I receptor antagonist
Catalog #: 2004

In stock

SKU-Size Size Price Qty
2004-25 25 mg
$90.00
2004-100 100 mg
$310.00
2004-500 500 mg
$1,025.00
More Sizes Get Quote

Product Details

Alternate Name (S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-pentanamido]butanoic acid; CGP-48933
Appearance White solid
CAS # 137862-53-4
Molecular Formula C₂₄H₂₉N₅O₃
Molecular Weight 435.52
Purity ≥98% by TLC
Solubility DMSO (~ 25 mg/ml)
SMILES CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)O
InChi InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1
InChi Key ACWBQPMHZXGDFX-QFIPXVFZSA-N
PubChem CID 60846
MDL Number MFCD00865840
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. A high affinity angiotensin I receptor antagonist (Ki = 2.38 nM). Clinically useful antihypertensive agent. Active in vivo. Also, a recent study has shown that Valsartan lowers brain β-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer’s disease.


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