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Valproic Acid, Sodium Salt

A HDAC1 inhibitor
Catalog #: 1647
$100.00

Product Details

Cat # +Size 1647-200
Size 200 mg
Alternate Name Valproic acid sodium, Sodium Valproate, VPA
Appearance White solid
CAS # 1069-66-5
Molecular Formula C₈H₁₅O₂.Na
Molecular Weight 166.19
Purity ≥98% by titration
Solubility H₂O (100 mM)
SMILES CCCC(CCC)C(=O)[O-].[Na+]
InChi InChI=1S/C8H16O2.Na/c1-3-5-7(6-4-2)8(9)10;/h7H,3-6H2,1-2H3,(H,9,10);/q;+1/p-1
InChi Key AEQFSUDEHCCHBT-UHFFFAOYSA-M
PubChem CID 16760703
MDL Number MFCD00078604
Handling Protect from air and moisture
Storage Conditions 4°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

A cell-permeable histone deacetylase 1 (HDAC1) inhibitor (IC₅₀ = 400 µM) that exhibits anticancer, anti-inflammatory and neuroprotective properties. Recently it has been reported that Valproic acid enables reprogramming of primary human fibroblasts with only two factors, Oct4 and Sox2, without the need for the oncogenes c-Myc or Klf4.


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