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Uteroglobin, human recombinant

Exerts anti-inflammatory and anti-tumorigenic effects
Catalog #: 7209
SKU-Size Size Price Qty
7209-10 10 μg
7209-50 50 μg
More Sizes Get Quote

Product Details

Alternate Name Clara cell phospholipid-binding protein, CCPBP, Clara cells 10 kDa secretory protein, CC10, Secretoglobin family 1A member 1, Urinary protein 1, UP-1, UP1, Urine protein 1
Gene Symbol SCGB1A1
Gene ID 7356
Accession # P11684
Source E. Coli
Appearance Lyophilized powder
Physical Form Description Sterile filtered through a 0.2 micron filter. Lyophilized from 1 X PBS.
Molecular Weight 8.0 kDa
Purity by SDS-PAGE ≥98%
Endotoxin Level < 0.1 ng/μg of protein (<1EU/μg).
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carri
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans


Uteroglobin, a member of the Secretoglobin superfamily, also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation. Recombinant Human Uteroglobin is an 8.0 kDa homodimeric protein consisting of 142 amino acid residues.

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