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USP7/USP47 Inhibitor

USP7-USP47 inhibitor is a dual inhibitor of ubiquitin-specific protease 7 (USP7) and USP47
Catalog #: B2538
SKU-Size Size Price Qty
B2538-1 1 mg
$85.00
B2538-5 5 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name 4-cyano-5-[(3,5-dichloro-4-pyridinyl)thio]-N-[4-(methylsulfonyl)phenyl]-2-thiophenecarboxamide
Peptide Sequence N/A
Appearance Crystalline solid
CAS # 1247825-37-1
Molecular Formula C₁₈H₁₁Cl₂N₃O₃S₃
Molecular Weight 484.4
Purity ≥ 98% by HPLC
Solubility >40 mg/ml in DMSO
SMILES CS(C1=CC=C(NC(C2=CC(C#N)=C(SC3=C(Cl)C=NC=C3Cl)S2)=O)C=C1)(=O)=O
InChi InChI=1S/C18H11Cl2N3O3S3/c1-29(25,26)12-4-2-11(3-5-12)23-17(24)15-6-10(7-21)18(27-15)28-16-13(19)8-22-9-14(16)20/h2-6,8-9H,1H3,(H,23,24)
InChi Key GUDJFFQZIISQJB-UHFFFAOYSA-N
PubChem CID 51031028
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

USP7/USP47 inhibitor is a dual inhibitor of ubiquitin-specific protease 7 (USP7) and USP47 (IC₅₀s = 0.42 and 1 μM, respectively). It is selective for USP7 and USP47 over USP2, USP5, USP8, USP21, USP28, caspase-3, and cathepsin B (IC₅₀s = >31.6 μM).


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