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USP3 Antibody

Polyclonal antibody to detect USP3 (a DUB enzyme) in human, mouse and rat samples.
Catalog #: 6142
$335.00

Product Details

Cat # +Size 6142-100
Size 100 μg
Antibody Target USP3
Alternate Name USP3, MGC129878, MGC129879, SIH003, UBP
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Fusion protein of human USP3
Accession # Q9Y6I4
Gene ID 9960
Appearance Colorless liquid
Formulation 100 µg of antibody in 100 µl PBS containing 0.02% sodium azide, 50% glycerol, pH 7.3
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot
Positive Control Western Blot: Various cell lysates
Application & Usage Western blot: 1:500 – 1:1000 dilution. However, the optimal conditions should be determined individually.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzymes (DUB) action. There are five DUB subfamilies including the USP, UCH, OTU, MJD, and JAMM enzymes. USP3 (ubiquitin specific peptidase3), also known as UBP or SIH003, is a 520 amino acid protein that contains one UBP­type zinc finger and belongs to the peptidase C19 family. Expressed ubiquitously with highest levels present in pancreas, USP3 catalyzes the conversion of a ubiquitin C­terminal thioester to a free ubiquitin and a thiol. The gene encoding USP3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome.


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