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Uprosertib

A selective, orally bioavailable Akt inhibitor
Catalog #: B1760

In stock

SKU-Size Size Price Qty
B1760-5 5 mg
$145.00
B1760-25 25 mg
$575.00
More Sizes Get Quote

Product Details

Alternate Name Uprosertib, GSK-2141795; GSK2141795; GSK 2141795; GSK795; GSK795; GSK 795; N-((S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)furan-2-carboxamide; N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methylpyrazol-3-yl)furan-2-carboxamide
Appearance Solid
CAS # 1047634-65-0
Molecular Formula C₁₈H₁₆Cl₂F₂N₄O₂
Molecular Weight 429.25
Purity >98%
Solubility DMSO
SMILES CN1C(=C(C=N1)Cl)C2=C(OC(=C2)C(=O)NC(CC3=CC(=C(C=C3)F)F)CN)Cl
InChi InChI=1S/C18H16Cl2F2N4O2/c1-26-16(12(19)8-24-26)11-6-15(28-17(11)20)18(27)25-10(7-23)4-9-2-3-13(21)14(22)5-9/h2-3,5-6,8,10H,4,7,23H2,1H3,(H,25,27)/t10-/m0/s1
InChi Key AXTAPYRUEKNRBA-JTQLQIEISA-N
PubChem CID 51042438
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Uprosertib, also known as GSK2141795 and GSK795, is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity.


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