Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

UNC0321 tri (trifluoroacetate salt)

An inhibitor of G9a HMTase
Catalog #: B2837
SKU-Size Size Price Qty
B2837-1 1 mg
B2837-5 5 mg
More Sizes Get Quote

Product Details

Alternate Name 7-(2-(2-(dimethylamino)ethoxy)ethoxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine, tri(trifluoroacetate) salt
Formulation A solution in methyl acetate
CAS # n/a
Molecular Formula C₃₃H₄₈F₉N₇O₉
Molecular Weight 857.76
Purity ≥95%
InChi InChI=1S/C27H45N7O3.3C2HF3O2/c1-31(2)15-16-36-17-18-37-25-20-23-22(19-24(25)35-5)26(28-21-7-11-33(4)12-8-21)30-27(29-23)34-10-6-9-32(3)13-14-34;3*3-2(4,5)1(6)7/h19-21H,6-18H2,1-5H3,(H,28,29,30);3*(H,6,7)
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


UNC0321 is an inhibitor of G9a histone methyltransferase (HMTase) with picomolar potency. It is a quinazoline analogue with a Morrison Ki of 63 pM. It inhibits G9a with an IC₅₀ of 6 nM and 9 nM in chemiluminescence-based oxygen tunneling (CLOT) assays and enzyme-coupled SAH detection assays (ECSD). It inhibits GLP (G9a like protein) with an IC₅₀ of 15 nM and 23 nM in these assays. It is inactive against SET7/9, SET8/PreSET7 and PRMT3 in ECSD assays.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.