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UNC-3866

A potent and selective antagonist of CBX4 and CBX7 chromodomains
Catalog #: B2361

In stock

SKU-Size Size Price Qty
B2361-5 5 mg
$125.00
B2361-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name N-[4-(1,1-dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine, methyl ester,UNC3866
Appearance Crystalline solid
CAS # 1872382-47-2
Molecular Formula C₄₃H₆₆N₆O₈
Molecular Weight 795.04
Purity ≥98%
Solubility DMSO
SMILES CCN(CC)CCCCC(C(=O)NC(CO)C(=O)OC)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=CC=C(C=C2)C(C)(C)C
InChi InChI=1S/C43H66N6O8/c1-10-49(11-2)24-16-15-19-33(39(53)48-36(27-50)42(56)57-9)45-41(55)34(25-28(3)4)46-37(51)29(5)44-40(54)35(26-30-17-13-12-14-18-30)47-38(52)31-20-22-32(23-21-31)43(6,7)8/h12-14,17-18,20-23,28-29,33-36,50H,10-11,15-16,19,24-27H2,1-9H3,(H
InChi Key UMRRDXVUROEIKJ-JCXBGQGISA-N
PubChem CID 101043861
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

UNC-3866 is a potent and selective antagonist of CBX4 and CBX7 chromodomains with (Kd ≈ 100 nM). It is 6- to 63-fold selective for these chromodomains over the other CBX and CDY chromodomains.


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