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UHRF2 Antibody

Polyclonal antibody to detect UHRF2 in human samples.
Catalog #: 6145
$335.00

Product Details

Cat # +Size 6145-100
Size 100 μg
Antibody Target UHRF2
Alternate Name NIRF, URF2, RNF107, RP11­472F14.2
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Recombinant protein of human UHRF2
Accession # Q96PU4
Gene ID 115426
Appearance Colorless liquid
Concentration 1 mg/ml
Formulation 100 µg of antibody in 100 µl PBS containing 0.02% sodium azide, 50% glycerol, pH 7.3
Purification Affinity purified
Species Reactivity Human
Application Western blot, Immunohistochemistry, Immunofluorescene
Positive Control Western Blot: Various cell lysates
Application & Usage Western blot: 1:500 – 1:2000, IHC: 1:50 – 1:200, IF: 1:20 – 1:50.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This gene encodes a nuclear protein which is involved in cell cycle regulation. The encoded protein is a ubiquitin ligase capable of ubiquinating PCNP (PEST­containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set­ and ring associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants, some of which are non­protein coding. [Provided by RefSeq, Feb 2012].


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