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UF 010

UF 010 is potent and selective class I HDAC inhibitor
Catalog #: B1146
SKU-Size Size Price Qty
B1146-10 10 mg
$95.00
B1146-50 50 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name 4-Bromo-N'-butylbenzohydrazide
Appearance White Solid
CAS # 537672-41-6
Molecular Formula C₁₁H₁₅BrN₂O
Molecular Weight 271.15
Purity ≥98% by HPLC
Solubility DMSO(>25 mg/ml)
SMILES CCCCNNC(=O)C1=CC=C(C=C1)Br
InChi 1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15)
InChi Key BVQCFCYPFJOOAV-UHFFFAOYSA-N
PubChem CID 4596836
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

UF 010 is class I HDAC inhibitor that displays >6- fold selectivity over other HDACs. It has an IC₅₀ value of 0.06, 0.1, and 1.5 μM for HDACs 3, 2, 1 and 8 respectively. In vitro experimental data shows accumulation of acetylated histones in HCT116 cells. UF 010 is known to arrest cells at G1/S transition inhibiting proliferation of various cancer cell lines.


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