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UBCS-039

The first synthetic SIRT6 activator
Catalog #: B2759
SKU-Size Size Price Qty
B2759-1 1 mg
$95.00
B2759-5 5 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name MC3154, UBCS039, 4-Pyridin-3-yl-4,5-dihydro-pyrrolo[1,2-a]quinoxaline, MC-3154
Peptide Sequence N/A
Appearance Crystalline solid
CAS # 358721-70-7
Molecular Formula C₁₆H₁₃N₃
Molecular Weight 247.29
Purity ≥98%
Solubility >60 mg/ml DMSO
SMILES C1=CC=C2C(=C1)NC(C3=CC=CN32)C4=CN=CC=C4
InChi InChI=1S/C16H13N3/c1-2-7-14-13(6-1)18-16(12-5-3-9-17-11-12)15-8-4-10-19(14)15/h1-11,16,18H
InChi Key BSOBGTYXYGHUTD-UHFFFAOYSA-N
PubChem CID 2803797
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

UBCS-039 is the first synthetic SIRT6 activator (EC50 = 38 μM); induces a time-dependent activation of autophagy in several human tumor cell lines. UBCS-039 induces deacetylation of SIRT6-targeted histone H3 sites in human cancer cells.


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