Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

UbcH3, human recombinant (His-tag)

An essential ubiquitin-conjugating enzyme
Catalog #: 4849
$350.00

Product Details

Cat # +Size 4849-100
Size 100 μg
Alternate Name UbcH3, Ubiquitin conjugating enzyme 3, Ubiquitin conjugating enzyme, Ubiquitin-conjugating enzyme E2-32 kDa complementing, Ubiquitin-conjugating enzyme E2-CDC34, Ubiquitin-protein ligase R1, CDC34, UBCH3, UBE2R1
Gene Symbol UB2R1
Gene ID 997
Accession # P49427
Source E. coli
Appearance Liquid
Physical Form Description Supplied at a concentration of 0.5 mg/ml in 50 mM HEPES, 50 mM NaCl, pH 8.0, containing 1.0 mM DTT.
Molecular Weight 32.0 kDa
Purity by SDS-PAGE ≥95%
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

UbcH3 is a class II enzyme, homologous to Cdc34 from Saccharomyces cerevisiae, and is important in the control of cell cycle and DNA replication. UbcH3/Cdc34 in association with different E3 complexes, including SCF, has been shown to target many different substrates for ubiquitination and degradation during cell division, signal transduction, and development. UbcH3 substrates that have been characterized include IκB, Wee1, ICERIIγ, p27Xic1. Additionally, substrates such as ß-catenin, p21, and is phosphorylated and ubiquitinylated in vivo.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.