Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Tyrphostin AG 490

An EGFR inhibitor
Catalog #: 1570
$100.00

Product Details

Cat # +Size 1570-5
Size 5 mg
Alternate Name 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(benzyl)-2-propenamide; 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide, AG 490
Appearance Off-white solid
CAS # 133550-30-8
Molecular Formula C₁₇H₁₄N₂O₃
Molecular Weight 294.31
Purity ≥99%
Solubility DMSO (100 mM) and ETOH (20 mM)
SMILES C1=CC=C(C=C1)CNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
InChi InChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+
InChi Key TUCIOBMMDDOEMM-RIYZIHGNSA-N
PubChem CID 5328779
MDL Number MFCD00236452
Handling Protect from light and air
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Selectively inhibits EGF receptor auto-phosphorylation (IC₅₀ = 100 µM) and selectively inhibits DNA synthesis and cell growth; induces apoptosis. A JAK2 inhibitor. Blocks growth of leukemia cells in vivo and in vitro.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.