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Product Details
| Cat # +Size | 3615-100 |
|---|---|
| Size | 100 µl |
| Antibody Target | Tyrosine Hydroxylase |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | SDS-denatured rat tyrosine hydroxylase, purified from pheochromocytoma. |
| Appearance | Colorless liquid |
| Formulation | 100 μl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50% glycerol. |
| Purification | Affinity purified |
| Species Reactivity | Mammalian |
| Application | Western blot, Immunoprecipitation, Immunofluorescence |
| Application & Usage | The antibody can be used for Western blotting (1:1000). However, the optimal conditions should be determined individually. |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drμg abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001; Dunkley et al., 2004).
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