TTNPB

A highly potent retinoic acid receptor (RAR) agonist
Catalog #: 2776 | abID:

Product Details

Alternate Name 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid; Ro 13-7410
Appearance White solid
CAS # 71441-28-6
Molecular Formula C₂₄H₂₈O₂
Molecular Weight 348.48
Purity ≥98%
Solubility DMSO (~8 mg/ml) or EtOH (~ 3 mg/ml)
SMILES CC(=CC1=CC=C(C=C1)C(=O)O)C2=CC3=C(C=C2)C(CCC3(C)C)(C)C
InChi InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+
InChi Key FOIVPCKZDPCJJY-JQIJEIRASA-N
PubChem CID 5289501
MDL Number MFCD00673917
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

TTNPB is a highly potent retinoic acid receptor (RAR) agonist (EC₅₀ = 21 nM, 4.0 nM, and 2.4 nM for RARα, RARβ, and RARγ, respectively). Enhances reprogramming efficiency in chemically induced pluripotent stem cells (CiPSCs).


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