Product Details
| Alternate Name | 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid; Ro 13-7410 |
|---|---|
| Appearance | White solid |
| CAS # | 71441-28-6 |
| Molecular Formula | C₂₄H₂₈O₂ |
| Molecular Weight | 348.48 |
| Purity | ≥98% |
| Solubility | DMSO (~8 mg/ml) or EtOH (~ 3 mg/ml) |
| SMILES | CC(=CC1=CC=C(C=C1)C(=O)O)C2=CC3=C(C=C2)C(CCC3(C)C)(C)C |
| InChi | InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+ |
| InChi Key | FOIVPCKZDPCJJY-JQIJEIRASA-N |
| PubChem CID | 5289501 |
| MDL Number | MFCD00673917 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
TTNPB is a highly potent retinoic acid receptor (RAR) agonist (EC₅₀ = 21 nM, 4.0 nM, and 2.4 nM for RARα, RARβ, and RARγ, respectively). Enhances reprogramming efficiency in chemically induced pluripotent stem cells (CiPSCs).
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