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Product Details
| Cat # +Size | A1024-100 |
|---|---|
| Size | 100 µg |
| Antibody Target | TNNT2 |
| Alternate Name | cTnT, TNNT2 |
| Host | Mouse |
| Antibody Type | Monoclonal |
| Isotype | Mouse IgG |
| Accession # | P45379 |
| Gene ID | 7139 |
| Appearance | Colorless liquid |
| Concentration | 1 mg/ml |
| Formulation | 100 ug (1mg/ml) of antibody in 0.01M Tris-HCl, pH 8.0, 0.15M NaCl, and 0.02% sodium azide. |
| Purification | Affinity purified mouse IgG using protein G |
| Species Reactivity | Human |
| Application | WB, ELISA, IHC |
| Application & Usage | ELISA: 1-5 µg/ml (Detection sensitivity 10 ng/ml), Immunocytochemistry: 5~10 µg/ml, Western Blot |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
The protein encoded by TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
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