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Anti-Troponin T Antibody (3G12)

Monoclonal antibody to detect Troponin T in human samples.
Catalog #: A1024
$295.00

Product Details

Cat # +Size A1024-100
Size 100 µg
Antibody Target TNNT2
Alternate Name cTnT, TNNT2
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG
Accession # P45379
Gene ID 7139
Appearance Colorless liquid
Concentration 1 mg/ml
Formulation 100 ug (1mg/ml) of antibody in 0.01M Tris-HCl, pH 8.0, 0.15M NaCl, and 0.02% sodium azide.
Purification Affinity purified mouse IgG using protein G
Species Reactivity Human
Application WB, ELISA, IHC
Application & Usage ELISA: 1-5 µg/ml (Detection sensitivity 10 ng/ml), Immunocytochemistry: 5~10 µg/ml, Western Blot
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The protein encoded by TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.


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