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Triciribine

An Akt inhibitor
Catalog #: 1707
$145.00

Product Details

Cat # +Size 1707-1
Size 1 mg
Alternate Name 1,5-Dihydro-5-methyl-1-b-D-ribofuranosyl-1,2,5,6,8-pentaazanaphthylen-3-amine; NSC 154020; Akt inhibitor V
Appearance Pale yellow solid
CAS # 35943-35-2
Molecular Formula C₁₃H₁₆N₆O₄
Molecular Weight 320.3
Purity ≥98% by HPLC
Solubility DMSO
SMILES CN1C2=NC=NC3=C2C(=CN3C4C(C(C(O4)CO)O)O)C(=N1)N
InChi InChI=1S/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/m1/s1
InChi Key HOGVTUZUJGHKPL-HTVVRFAVSA-N
PubChem CID 65399
MDL Number MFCD16879015
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. A synthetic tricyclic nucleoside which acts as a specific inhibitor of the Akt signaling pathway. It selectively inhibits the phosphorylation and activation of Akt1, -2 and -3 but does not inhibit Akt kinase activity nor known upstream Akt activators such as PI 3-Kinase and PDK1.


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