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TREM1, human recombinant

Amplifies neutrophil and monocyte-mediated inflammatory responses
Catalog #: 7332
$295.00

Product Details

Cat # +Size 7332-100
Size 100 μg
Alternate Name Triggering receptor expressed on myeloid cells 1, CD354, TREM-1
Gene Symbol TREM1
Gene ID 54210
Accession # Q9NP99
Source E. coli
Appearance Liquid
Physical Form Description 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 30% glycerol and 1 mM DTT.
Molecular Weight 23.3 kDa (209 aa, 21-205 aa + His Tag), confirmed by MALDI-TOF.
Purity by SDS-PAGE ≥85%
Endotoxin Level < 1.0 EU per 1 microgram of protein
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSM ATKLTE EKYELKEGQT LDVKCDYTLE KFASSQKAWQ IIRDGEMPKT LACTERPSKN SHPVQVGRII LEDYHDHGLL RVRMVNLQVE DSGLYQCVIY QPPKEPHMLF DRIRLVVTKG FSGTPGSNEN STQNVYKIPP TTTKALCPLY TSPRTVTQAP PKSTADVSTP DSEINLTNVT DIIRVPVFN
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

TREM1 is a receptor belonging to the Ig super family that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. Recombinant human TREM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


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