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A potent second-generation Pim kinase inhibitor
Catalog #: B2229
SKU-Size Size Price Qty
B2229-5 5 mg
B2229-25 25 mg
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Product Details

Alternate Name 2-((1R,4R)-4-((3-(3-(trifluoromethyl)phenyl)imidazo[1,2-b]pyridazin-6-yl)amino)cyclohexyl)propan-2-ol
Appearance White to off-white solid
CAS # 1361951-15-6
Molecular Formula C₂₂H2₂₅F₃N₄O
Molecular Weight 418.46
Purity ≥98% by HPLC
Solubility DMSO
InChi InChI=1S/C22H25F3N4O/c1-21(2,30)15-6-8-17(9-7-15)27-19-10-11-20-26-13-18(29(20)28-19)14-4-3-5-16(12-14)22(23,24)25/h3-5,10-13,15,17,30H,6-9H2,1-2H3,(H,27,28)
PubChem CID 66598080
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


TP-3654 is a second-generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim-1 and Pim-3, respectively. Displays anticancer activities.

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