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TOFA

An allosteric acetyl Co-A carboxylase (ACC1) inhibitor
Catalog #: B2167

In stock

SKU-Size Size Price Qty
B2167-5 5 mg
$95.00
B2167-25 25 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name 5-(tetradecyloxy)-2-furancarboxylic acid; RM14514
Appearance White to off-white solid
CAS # 54857-86-2
Molecular Formula C₁₉H₃₂O₄
Molecular Weight 324.5
Purity ≥98%
Solubility DMSO (~2 mg/ml)
SMILES CCCCCCCCCCCCCCOC1=CC=C(O1)C(=O)O
InChi InChI=1S/C19H32O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22-18-15-14-17(23-18)19(20)21/h14-15H,2-13,16H2,1H3,(H,20,21)
InChi Key CZRCFAOMWRAFIC-UHFFFAOYSA-N
PubChem CID 115175
MDL Number NFCD01726059
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

TOFA is an allosteric inhibitor of acetyl Co-A carboxylase (ACC1). TOFA blocks fatty acid synthesis and Induces apoptosis in a dose-dependent manner. Stimulates neurite outgrowth and neuronal differentiation in rat pheochromocytoma cells. TOFA impairs glucose-stimulated insulin secretion after chronic treatment.


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