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An aminoglycoside antibiotic
Catalog #: B1537

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SKU-Size Size Price Qty
B1537-100 100 mg
B1537-500 500 mg
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Product Details

Alternate Name O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1-6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1-4)]-2-deoxy-D-streptamine
Appearance White solid
CAS # 32986-56-4
Molecular Formula C₁₈H₃₇N₅O₉
Molecular Weight 467.52
Purity ≥94%(Titration)
Solubility H₂O (>45 mg/ml)
InChi InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1
PubChem CID 36294
MDL Number MFCD00077885
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Tobramycin is an aminoglycoside antibiotic that binds irreversibly to one of two aminoglycoside binding sites on the 30S ribosomal subunit, inhibiting bacterial protein synthesis. Tobramycin may also destabilize bacterial membranes by binding to 16S rRNA (ribosomal RNA). It inhibits translocation and elicits miscoding. Tobramycin is used to treat Pseudomonas aeruginosa lung infections and is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis, and other soft-tissue infections.

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