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TNFRSF6B, human recombinant

Acts as a decoy receptor that competes with death receptors for ligand binding
Catalog #: 7329
$295.00

Product Details

Cat # +Size 7329-100
Size 100 μg
Alternate Name Tumor necrosis factor receptor superfamily member 6B
Gene Symbol TNFRSF6B
Gene ID 8771
Accession # O95407
Source E. coli
Appearance Liquid
Physical Form Description 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol and 2 M Urea
Molecular Weight 32.1 kDa (294 aa, 30-300 aa + His Tag), confirmed by MALDI-TOF.
Purity by SDS-PAGE ≥85%
Endotoxin Level < 1.0 EU per 1 microgram of protein
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSVAETPTY PWRDAETGER LVCAQCPPGT FVQRPCRRDS PTTCGPCPPR HYTQFWNYLE RCRYCNVLCG EREEEARACH ATHNRACRCR TGFFAHAGFC LEHASCPPGA GVIAPGTPSQ NTQCQPCPPG TFSASSSSSE QCQPHRNCTA LGLALNVPGS SSHDTLCTSC TGFPLSTRVP GAEECERAVI DFVAFQDISI KRLQRLLQAL EA
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

TNFRSF6B belongs to Tumor necrosis factor receptor superfamily. It acts as a decoy receptor that competes with death receptors for ligand binding. This protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. Recombinant human TNFRSF6B protein, fused to His-tag at N-terminus, was expressed in E.coli.


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