You have no items in your shopping cart.
Product Details
| Alternate Name | Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2 |
|---|---|
| Gene Symbol | TNFA |
| Gene ID | 7124 |
| Accession # | P01375 |
| Source | E. coli. |
| Appearance | Lyophilized powder |
| Physical Form Description | Lyophilized in 50 mM Tris, 150 mM NaCl pH 8.5 |
| Molecular Weight | 17.4 kDa |
| Purity by SDS-PAGE | ≥98% |
| Purity by | ≥98% |
| Biological Activity | ED50 < 0.05 ng/ml as determined by the cytolysis of murine L929 cells in the presence of actinomycin D. |
| Reconstitution Instructions | Reconstitute in H₂O to a concentration of 1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Tumor Necrosis Factor-α(TNF-α) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. Human TNF-α is a 17.4 kDa protein containing 157 amino acid residues.
Why buy BioVision Products?
 |
 |
 |
 |
Innovation |
Affordability |
Global Presence |
Technical Support |
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways. |
BioVision is committed to providing the highest quality products at a competitive price. |
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery. |
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently. |
Hui et al., Individual Cytokines Modulate the Neurological Symptoms of ATMDeficiency in a Region Specific Manner. eNeuro, Jul 2015; 2: ENEURO.0032-15.2015
Wang et al., Herpes Simplex Virus 1 Protein Kinase US3 Hyperphosphorylates p65/RelA and Dampens NF-
B Activation. J. Virol., Jul 2014; 88: 7941 - 7951.
B Activation. J. Virol., Jul 2014; 88: 7941 - 7951.Zhang et al., Herpes Simplex Virus 1 E3 Ubiquitin Ligase ICP0 Protein Inhibits Tumor Necrosis Factor Alpha-Induced NF-B Activation by Interacting with p65/RelA and p50/NF-
B1. J. Virol., Dec 2013; 87: 12935 - 12948.
B Activation by Interacting with p65/RelA and p50/NF-B1. J. Virol., Dec 2013; 87: 12935 - 12948.Zheng, Z. et. al. Enterovirus 71 2C Protein Inhibits TNF-α–Mediated Activation of NF-
B by Suppressing I
B Kinase β Phosphorylation. J. Immunol., Sep 2011; 187: 2202 - 2212.
B by Suppressing IB Kinase β Phosphorylation. J. Immunol., Sep 2011; 187: 2202 - 2212.Bhola, P, Simon, S. Determination and Divergence of Apoptosis Susceptibility in Mammalian Cells. J. Cell Sci. 2009; 122: 4296-4302.
For more citations of this product click here
